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JOHN POLIO, M.D. |
| EDUCATION: |
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1975 – 1979
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Boston University School of Medicine
Boston, MA - M.D. Degree |
1971 – 1975
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College of the Holy Cross
B.A. Degree, Cum Laude |
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| LICENSURE: |
Medical Licensure |
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| BOARD CERTIFICATIONS: |
| 1983 |
American Board of Internal Medicine |
| 1985 |
American Board of Internal Medicine
Subspecialty Gastroenterology |
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HONORS & AWARDS: |
| 1994, 1998 |
Thomas R. Preston Award of Excellence in Teaching
University of Connecticut, St. Francis Hospital |
| 1986 – 1989 |
Associative Investigator Grant. Veterans Administration |
| 1985 |
American Liver Foundation Postdoctoral Research Fellowship |
| 1979 |
Henry Bakst Award for Clinical Excellence.
Boston University School of Medicine |
| 1975 |
Phi Beta Kappa. College of the Holy Cross |
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| EMPLOYMENT EXPERIENCE: |
| Practice: |
| July 1996 - Present |
Connecticut Gastroenterology Associate
Hartford, CT |
January 1988 -
June 1996 |
Hartford Gastroenterology Associates, P.C.
Hartford, CT |
Faculty: |
| January 2001 |
Medical Co-Director, Liver Transplantation
Hartford Hospital |
| January 1996 |
Associate Clinical Professor of Medicine
Department of Medicine
University of Connecticut Health Center Farmington, CT and St. Francis Hospital and Medical Center, Hartford, CT |
January 1988 -
December 1995 |
Assistant Clinical professor of Medicine
Department of Medicine
University of Connecticut Health Center, Farmington, CT and
St. Francis Hospital and Medical Center, Hartford, CT |
January 1988-
1999 |
Assistant Clinical Professor of Medicine
Department of Medicine
Yale University School of Medicine, New Haven, CT |
July 1987 -
December 1987 |
Assistant Professor of Medicine,
Department of Medicine, Digestive Disease Unit,
Yale University School of Medicine, New Haven, CT and
West Haven VA Medical Center, West Haven, CT |
July 1986 -
June 1987 |
Instructor, Department of Medicine (R.M. Donaldson, M.D., Acting Chairman), Digestive Disease Unit |
Fellowship: |
July 1983 -
June 1986 |
Fellow, Digestive Disease Unit
(J.L. Boyer, M.D., Chief),
Yale University School of Medicine, New Haven, CT |
Research: |
September 1984 - June 1986 |
Hepatic Hemodynamics Laboratory
(R.J. Groszmann, M.D.),
West Haven Veterans Administration Hospital,
West Haven, CT |
Residency: |
July 1982 –
June 1983 |
Chief Resident, Department of Internal Medicine
(R.B. Hornick, M.D., Chairman),
Strong Memorial Hospital, Rochester, N.Y. |
June 1979 –
June 1982 |
Resident, Department of Internal Medicine
Strong Memorial Hospital, Rochester, N.Y. |
| Related Experience: |
| 2002 - 2004 |
Reviewer Hepatology, Reviewer
Journal Clinical Gastroenterology |
January 1983 -
June 1983 |
Nutritional Support Service (Wm. Klish, M.D.), inpatient and outpatient consultative service.
Strong Memorial Hospital, Rochester, N.Y |
July 1976 - September 1976 |
Lahey Clinic Foundation (R.A. Oberfield, M.D.)
Study of percutaneous intra-arterial hepatic Infusion for treatment of hepatic metastases of primary colorectal carcinoma. |
| April 1978 |
Mallory Institute of Pathology (M. O’Brien, M.D.) Boston, MA, Review of autopsy cases of hepatoma at Boston City Hospital |
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| PUBLICATION: Abstracts |
Polio J, Hanson J, Sikuler E, Vogel G, Fisher R, Groszmann RJ: Endoscopic measurement of variceal pressure: In vivo and In vitro evaluation of a pressure sensitive capsule. Hepatology 1985; 5(5):1057 |
Polio J, Hanson J, Sikuler E, Vogel G, Fisher R, Groszmann RJ: A critical assessment of a pressure sensitive capsule for the endoscopic measurement of variceal pressure. Gastroenterology 1986; 90:5(2):1757 |
Polio J, Groszmann RJ: A rat model of portal hypertension resisitant to the portal pressure lowering effect of Propranolol and Nitroglycerin. Presented at the 37th annual meeting of the AASLD in Chicago, IL. Hepatology 1986; 6(5):1179.
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Polio J, Better OS, Sterzel RB, Reuben A, and Groszmann RJ: Renal hyperfusion and natriuresis in a rat model of portel hypertension: Relationship to arterial bile acid levels. Hepatology 1986; 6(5):1179
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Better OS, Polio J, Reuben A, Groszmann RJ, Sterzel B: Renal hyperfusiosn and impaired sodium conservation in rats with prehepatic portal hypertension. Presented at the ASN meeting in Washington, D.C. Kid Int 31:420, 1987 |
Leonard R, Polio J, Vogel G, Groszmann RJ: An improved pressure sensitive capsule for the endoscopic measurement of esophageal variceal pressure (EVP). Presented at the AGA meeting in Chicago, IL. Gastroenterology 1987; 92:1501.
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Polio J, Groszmann RJ: Primary increase in portal pressure in a genetic rat model of arterial hypertension. Hepatology 1987; 7(5):1059 |
Polio J, Better OS, Sterzel B, Reuben A, Groszmann RJ: Portal hypertension reverses arterial hypertension in spontaneously hypertensive rats. Presented at the AASLD meeting in Chicago, IL.
Hepatology 1987; 7(5):1102
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Polio J, Groszmann RJ: Increased intrahepatic resistance in a genetic rat model of arterial hypertensions: Studies in isolated perfused rat liver. Presented at the Digestive Disease Week meeting in New Orleans. Gastroenterology 1988; 94(5) (Part 2):A357.
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Genecin P, Polio J, Reuben A, Groszmann RJ: Normalization of serum bile acid levels with cholestyramine fails to ameliorate the hyperdynamic circulation in portal hypertensive rats. Presented at the 39th meeting of the AASLD in Chicago, IL.
Hepatology 1988; 8(5):1220
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Genecin P, Polio J, Groszmann RJ: Sodium intake modulates portal pressure and the hyperdynamic circulation in portal hypertensive rats. Presented at the AGA meeting in Washington, DC
Gastroenterology 1989; 96(5):A599 |
Colombato LA, Polio J, Kaumann AJ, Groszmann RJ: Hyporesponsiveness of the intrahepatic portal circulation to Norepinephrine in the isolated perfused liver of spontaneously hypertensive rats. Presented at Digestive Disease Week meeting in New Orleans. Gastroenterology 1991.
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PUBLICATION: Abstracts (Continued) |
Sieber C, Polio J, Lerner E, Groszmann RJ: Hyporesponsiveness to Norepinephrine in normal and portal ypertensive mature rats. Presented at Digestive Disease Week meeting in San Francisco. Gastroenterology 1992; 102(4):242A. |
Polio J, St. Louis T, Tummillo K, etal.: The Efficacy of an Interferon Dose Escalation Scheme, Combined with Ribavirin, for the Treatment of Interferon Refractory Hepatitis C: An Analysis of End of Treatment and Sustained Virologic Response. Presented at SHINE meeting, Orlandi, Florida, 2001 |
Levanthal R, St. Louis T, Tummillo K, Polio J, etal.: The Efficacy of an Interferon Dose Escalation Scheme, Combined with Ribavirin, for the Initial Treatment of Hepatitis C: An Analysis of End of Treatment and Sustained Virologic Response. Presented at SHINE meeting, Orlando, Florida, 2001. |
Krawitt EL, Lidofsky SD, Ferrentino, N et al: Efficacy of PEG Interferon Alpha-2B plus Ribavirin in patients with chronic hepatitis C previously unresponsive to Interferon-based therapy. Presented at AASLD in Boston, MA Hepatology 2002; 36:359A. |
Krawitt EL, Grace MD, Gordon SR et al: Compaarison of Low Dose with Standard Dose PEG Interferon Alpha 2b plus Ribavirin for Initial Treatment of Chronic Hepatitis C. Presented at AASLD in Boston, MA Hepatology 20003. |
White CL, Molet PF, Wentworth CL et al: Interferon Results Comparing 1.5 ng/kg vs 3.0mg/kg Pegylated Interferon Alpha 2b (PEG) plus Ribavirin (RBV) for Genotype Patients. Presented at AASLD in Boston, MA Hepatology 2003. |
Oberfield RA, McCaffrey JA, Polio J, Clouse ME, Hamilton TT: Prolonged and continuous percutaneous intra-arterial Hepatic infusion chemotherapy in advanced metastatic liver adenocarcinoma from colorectal primary. Cancer 1979; 44:414-423. |
Bordley DR, Mushlin AI, Dolan JG, Richardson WS, Barry M, Polio J, Griner PF: Early clinical signs identify low-risk patients with acute gastroenterological hemorrhage. JMA 1985; 253:3283-3285. |
Polio J and Groszmann RJ: Hemodynamic factors involved in the development and rupture of esophageal varices: A physiological approach to treatment. Seminars Liver Disease 1986; Nov. 6(4):318-331 |
Polio J, Hanson J, Sikuler E, Vogel G, Gusberg R, Fisher R, Groszmann RJ: A critical evaluation of a pressure sensitive capsule for measurement of esophageal varix pressure: Studies in vitro and in canline mesenteric vessels. Gastroenterology 1987; 92:109-115 |
Groszmann RJ and Polio J; Pathophysiiological mechanisms in esophageal variceal rupture. In: Methodology and reviews of Clinical Trials in Portal Hypertension (Burroughs, AK editor) 1987; 263-270 |
Sikuler E, Polio J, Groszmann RJ, Hendler R: Glucagon and insulin metabolism in a portal hypertensive rat model. Am J Physiol. 1987; 253 (Gastrointest.Liver Physiol. 16):G110-G115 |
Polio J, Enriquez RE, Chou A, Wood WM: Hepatocellular carcinoma as a complication of Wilson’s disease. Case report and review of literature. J. Clinical Gastro. 1989; 8:220-224 |
Polio J, Leonard R, Groszmann RJ, Vogel G: An improved pressure sensitive capsule for the measurement of esophageal variceal pressure. Dig Dis Sci 1988; 33(6)737-740 |
Polio J, Groszmann RJ, Reuben A, Sterzel RB, Better OS: Portal hypertension ameliorates arterial hypertension in spontaneously hypertensive rats. J. Hepatology 1989; 8:294-301 |
Fritz H, Polio J, Hewitt K: Biloma as a complication of hepatocellular carcinoma in an HIV-seropositive patient. Amer. J. Gastro.
1989; 84(12):1560-15563 |
Polio J, Groszmann RJ: Bleedng esophageal varices. Practical Gastro. 13 (8)41, 1989 |
Genecin P, Polio J, Colombato L, Ferraioli G.,, Reuben A, Groszmann RJ: Bile acids do not mediate the hyperdydnamic circulation in aportal hypertensive ratss. Am J Physiol. 1990; 259 (Gastrointest. Liver Physiol. 22):G21-G25 |
Genecin P, Polio J, Groszmann RJ: Sodium Intake modulates portal pressure and the hyperdynamic circulation in portal hypertensive rates. Am J Physiol. 1990;259:G498-G503 |
Colombato L, Sabba C, Polio J, Groszmann RJ: Influence of the post anesthesia state and restraint on superior mesenteric blood flow in normal rats: Am J Physiol. 1991;260 (Gastrointest. Liver Physiol. 23):G1-G6 |
Polio J, Sieber C, Lerner E, Groszmann RJ: Vascular hyporesponsiveness to Norepinephrine, Propanolol, and Nitroglycerin in normal and portal hypertensive mature rats. Hepatology 1993, 18(1):128-136 |
| Polio J, Groszmann RJ: Pharmacological control of portal hypertension. In: Progress in Liver Disease (Boyer J, Ockner R, editors) 1993; Vol. XI:231-249 |
| Ferayorni L, Polio J, Groszmann RJ: Drug therapy for portal hypertension: A 5-year review. In: Portal Hypertension II Proceedings of the Second Bavero International Consensus Workshop on definitions, Methodology and Therapeutic Strategies. De Franchis, R.ed. Blackkwell Scientific 1996, 66-97 |
| Polio J, Groszmann RJ, Taylor MB: Acute management of portal hypertensive hemorrhage from the upper gastrointestinal tract. In: Gastrointestinal Emergencies (2nd edition), Taylor MB, ed, Williams and Wilkins 1997, 131-150 |
| Kozarek RA, Raltz S, Marcon N, et al: Prospective multi-center trial using 25 mm flanged esophageal Z stent for malignant dysphagia. Gastrointestinal Endoscopy 1997, 46:156-60 |
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